{"id":283,"date":"2023-02-01T12:31:35","date_gmt":"2023-02-01T10:31:35","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=283"},"modified":"2025-05-17T02:18:11","modified_gmt":"2025-05-16T23:18:11","slug":"apraclonidine-dose","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/apraclonidine-dose\/","title":{"rendered":"Apraclonidine"},"content":{"rendered":"<div class=\"vet-drug-content\">\n<p style=\"font-family: sans-serif; font-size: 19px; text-align: center; font-weight: 600;\">Apraclonidine for Dogs: Dosage, Uses, and Side Effects Guide<\/p>\n<div class=\"vet-drug-image-container\"><img decoding=\"async\" class=\"vet-drug-img\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2025\/03\/apraclonidine-for-dogs-dosage-uses-and-side-effects-guide.jpg\" alt=\"Apraclonidine for Dogs: Dosage, Uses, and Side Effects Guide\" \/><\/div>\n<div class=\"vet-drug-buttons\"><a class=\"vet-drug-btn\" href=\"#vet-drug-dosage\">Drug Dosages<\/a><br \/>\n<a class=\"vet-drug-btn\" href=\"#vet-drug-uses\">Drug Uses<\/a><\/div>\n\n<h2 id=\"vet-drug-overview\" class=\"cd-section-title\">Overview<\/h2>\n<p>Apraclonidine is a Topical <strong>alpha-2-selective agonist<\/strong> that decreases aqueous humour production by inhibition of adenylate cyclase activity in the ciliary body.<\/p>\n<p><strong>Formulations:<\/strong> <em><strong>Ophthalmic:<\/strong> <\/em>0.5% solution (5 ml bottle); preservative-free 1% solution (single-dose vials).<\/p>\n<div class='code-block code-block-20' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 id=\"vet-drug-uses\" class=\"cd-section-title\">Uses of Apraclonidine<\/h2>\n<p><strong>Main Apomorphine Uses in Dogs:<\/strong><\/p>\n<ul>\n<li>Reducing intraocular pressure in <strong>glaucoma<\/strong>; however, effect in dogs is inconsistent and it is\u00a0unlikely to be effective as the sole agent in most forms of canine glaucoma.<\/li>\n<li>It may be most useful in<strong> alleviating pressure<\/strong> rises after intraocular surgery.<\/li>\n<\/ul>\n<h2 id=\"vet-drug-dosage\" class=\"cd-section-title\">Dosage of Apraclonidine<\/h2>\n<h3 style=\"color: #327f85;\"><strong>Dosage in Dogs:<\/strong><\/h3>\n<p><strong>1 drop<\/strong> per eye q8\u201312h for short-term use only.<\/p>\n<\/div>\n<div class=\"vet-drug-content\">\n<h3 style=\"color: #327f85;\"><strong>Dosage in Cats &amp; Other Animals:<\/strong><\/h3>\n<p>Do not use.<\/p>\n<div class='code-block code-block-30' style='margin: 8px 0; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fabd14 solid;font-size: 20px;\" id=\"cd-understanding\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 id=\"vet-drug-side-effects\" class=\"cd-section-title\">Side Effects of Apraclonidine in Dogs<\/h2>\n<p><strong>Common Apraclonidine Side Effects:<\/strong><\/p>\n<ul>\n<li>Causes blanching of conjunctival vessels and bradycardia<strong> in dogs and cats. <\/strong><\/li>\n<li>Causes mydriasis <strong>in dogs<\/strong>, miosis and severe vomiting <strong>in cats.<\/strong><\/li>\n<\/ul>\n<h2 id=\"vet-drug-contraindications\" class=\"cd-section-title\">Contraindications of Apraclonidine<\/h2>\n<p><strong>Important Apraclonidine Contraindications To Consider:<\/strong><\/p>\n<ul>\n<li>Commercial preparations are considered too toxic for use in cats.<\/li>\n<li>Do not use in dogs with uncontrolled cardiac disease.<\/li>\n<\/ul>\n<h2 id=\"vet-drug-notes\" class=\"cd-section-title\">Important Notes<\/h2>\n<ol>\n<li>It is prudent to monitor <strong>heart rate<\/strong> before and after topical application of apraclonidine, particularly with initial use and in small dogs.<\/li>\n<li>To limit systemic absorption, <strong>raise head and compress lower nasolacrimal punctum for every topical administration.<\/strong><\/li>\n<\/ol>\n<div class=\"vet-drug-footer\">\ud83d\udcd6 **References available upon request** | \ud83d\udd0d Last updated: 23-1-2022<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Apraclonidine for Dogs: Dosage, Uses, and Side Effects Guide Drug Dosages Drug Uses Overview Apraclonidine is a Topical alpha-2-selective agonist that decreases aqueous humour production by inhibition of adenylate cyclase activity in the ciliary body. Formulations: Ophthalmic: 0.5% solution (5 ml bottle); preservative-free 1% solution (single-dose vials). Uses of Apraclonidine Main Apomorphine Uses in Dogs: [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":1061,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[44],"tags":[42,43],"class_list":["post-283","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-ophthalmic-drugs","tag-alpha-adrenergic","tag-anti-glaucoma-agent"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/283","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=283"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/283\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1061"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=283"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=283"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=283"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}