{"id":280,"date":"2023-02-01T12:27:15","date_gmt":"2023-02-01T10:27:15","guid":{"rendered":"https:\/\/www.vetdrugslist.com\/?p=280"},"modified":"2025-05-17T02:15:58","modified_gmt":"2025-05-16T23:15:58","slug":"apomorphine-dose","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/apomorphine-dose\/","title":{"rendered":"Apomorphine"},"content":{"rendered":"
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Apomorphine for Dogs: Dosage, Uses, and Side Effects Guide<\/p>\n

\"Apomorphine<\/div>\n
Drug Dosages<\/a>
\nDrug Uses<\/a><\/div>\n\n

Overview<\/h2>\n

Apomorphine is mainly For dogs to induce vomiting and works quickly by stimulating dopamine receptors in the brain. In most cases, it causes vomiting within a few minutes, especially when given by injection. For Cats, it\u2019s not used as it\u2019s usually not effective for them and we can use dexmedetomidine instead.<\/span><\/p>\n

There are some important cases where apomorphine shouldn\u2019t be used \u2014 such as in animals that can\u2019t vomit (like rabbits and rodents) or if vomiting could cause harm, for example, after swallowing corrosive substances or in animals with seizures or at risk of aspiration. Because of potential health risks to people handling it, apomorphine is considered hazardous and should be handled carefully, following proper safety steps.
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\n\"Vet<\/a><\/div>\n\n

Uses of Apomorphine<\/h2>\n

Main Apomorphine Uses in Animals:<\/strong><\/p>\n

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  • Dogs:<\/strong> Apomorphine for dogs is a potent emetic used after ingestion of toxins or foreign bodies. It is effective in about 90%\u2013100% of cases and is most beneficial when given within 2 hours of ingestion. Prompt use can help prevent absorption of harmful substances.<\/li>\n
  • Cats:<\/strong> Apomorphine is generally avoided in cats due to poor effectiveness and potential safety concerns. Alpha-2 agonists like dexmedetomidine are preferred for inducing emesis in feline patients.<\/li>\n
  • Contraindicated species:<\/strong> Apomorphine should not be used in species unable to vomit (e.g., rabbits, rodents) or in cases where vomiting could cause harm (e.g., seizures, coma, corrosive ingestion).<\/li>\n<\/ul>\n
    Note:<\/strong> Vomiting usually removes only 40%\u201360% of stomach contents. Even after emesis, further treatment and monitoring are often necessary.<\/div>\n

    Dosage of Apomorphine<\/h2>\n

    Dosage in Dogs (Extra-label Use)<\/strong><\/h3>\n

    Apomorphine injection For Dogs Is Given:<\/strong><\/p>\n

      \n
    • Intravenous (IV):<\/strong> 0.01 \u2013 0.04 mg\/kg \u2013 induces vomiting rapidly, often within 1\u20135 minutes.<\/li>\n
    • Subcutaneous (SC):<\/strong> 0.01 \u2013 0.04 mg\/kg \u2013 effective emesis occurs within 13.5 minutes on average (range: 3\u201332 minutes).<\/li>\n
    • Intramuscular (IM):<\/strong> 0.01 \u2013 0.04 mg\/kg \u2013 slowest onset compared to IV and SC routes.<\/li>\n<\/ul>\n

      Apomorphine Oral (PO):<\/strong> 0.25 mg\/kg \u2013 approximately one 6.5 mg tablet per 26 kg body weight. Efficacy may vary.<\/p>\n<\/div>\n

      Apomorphine Subconjunctival:<\/strong> Place a 6.25 mg tablet (whole or crushed) under the conjunctiva or dissolve in saline and instill into the eye. Rinse thoroughly after vomiting to prevent prolonged emesis.<\/p>\n

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      Dosage in Ferrets (Extra-label Use)<\/strong><\/h3>\n
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      • IV, IM, or SC:<\/strong> 0.04 mg\/kg<\/li>\n
      • Subconjunctival:<\/strong> 0.25 mg\/kg<\/li>\n<\/ul>\n
        Important:<\/strong> Always monitor animals closely after administration. If emesis does not occur promptly, do not repeat the dose. Prolonged vomiting can be managed with antiemetics such as maropitant or metoclopramide.<\/div>\n
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