{"id":2634,"date":"2024-02-05T21:29:29","date_gmt":"2024-02-05T19:29:29","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2634"},"modified":"2024-02-03T21:32:33","modified_gmt":"2024-02-03T19:32:33","slug":"sucralfate","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/sucralfate\/","title":{"rendered":"Sucralfate"},"content":{"rendered":"

Sucralfate In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Sucralfate$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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In an acidic medium, aluminum ion detachment occurs from the compound.<\/li>\n
The detached ion is very polar and relatively non-absorbable.<\/li>\n
This ion binds to proteinaceous exudates in the upper GI tract.<\/li>\n
Forms a chemical diffusion barrier over ulcer sites, preventing further erosion from acid, pepsin, and bile salts.<\/li>\n
Major action involves stimulating mucosal defenses and repair mechanisms.<\/li>\n
Stimulation includes bicarbonate and PGE production and binding of epidermal growth factor.<\/li>\n
These effects are observed at neutral pH.<\/li>\n<\/ul>\n
Uses of Sucralfate<\/strong><\/h2>\n
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Treatment of oesophageal, gastric and duodenal ulceration.<\/li>\n
The efficacy of sucralfate as a phosphate binder in renal failure is uncertain.<\/li>\n
Can be used alongside an H2 receptor antagonist or proton-pump inhibitor but should be given separately.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Sucralfate in Dogs and Cats<\/strong><\/h2>\n
Dogs: <\/strong><\/p>\n
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All uses<\/strong><\/span>: 500 mg\/dog p.o. q6\u20138h (dogs up to 20 kg); 1\u20132 g\/ dog p.o. q6\u20138h (>20 kg).<\/li>\n<\/ul>\n
Cats: <\/strong><\/p>\n
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All uses<\/strong><\/span>: 250 mg\/cat p.o. q8\u201312h.<\/li>\n<\/ul>\n
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