{"id":2584,"date":"2024-04-15T03:24:47","date_gmt":"2024-04-15T01:24:47","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2584"},"modified":"2024-04-15T03:24:47","modified_gmt":"2024-04-15T01:24:47","slug":"pyrimethamine","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/pyrimethamine\/","title":{"rendered":"Pyrimethamine"},"content":{"rendered":"

Pyrimethamine In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Pyrimethamine$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Interference with folate metabolism of the parasite and thereby prevents purine synthesis (and therefore DNA synthesis).<\/li>\n<\/ul>\n
Uses of Pyrimethamine<\/strong><\/h2>\n
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Treatment of infections caused by Toxoplasma gondii and Neospora caninum.<\/li>\n
Should not be used in pregnant or lactating animals without adequate folate supplementation.<\/li>\n<\/ul>\n
Dose of Pyrimethamine in Dogs and Cats<\/strong><\/h2>\n
Dogs, Cats: <\/strong><\/p>\n
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Toxoplasmosis\/neosporosis<\/strong><\/span>: 1 mg\/kg p.o. q24h or divided q12h for 4 weeks, alongside sulphonamides.<\/li>\n<\/ul>\n
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