{"id":2455,"date":"2023-12-25T14:10:01","date_gmt":"2023-12-25T12:10:01","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2455"},"modified":"2023-12-25T14:10:01","modified_gmt":"2023-12-25T12:10:01","slug":"pilocarpine","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/pilocarpine\/","title":{"rendered":"Pilocarpine"},"content":{"rendered":"

Pilocarpine In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Pilocarpine$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Direct-acting parasympathomimetic<\/strong> that stimulates cholinergic receptors.<\/li>\n
It lowers intraocular pressure by causing ciliary body muscle contraction, miosis and improved aqueous humour outflow.<\/li>\n<\/ul>\n
Uses of Pilocarpine<\/strong><\/h2>\n
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Pilocarpine, once employed in glaucoma treatment<\/strong>, has been overshadowed by other topical drugs like carbonic anhydrase inhibitors and prostaglandin analogues.<\/li>\n
It induces pupil constriction (miosis)<\/strong> within 10\u201315 minutes, persisting for 6\u20138 hours in dogs.<\/li>\n
Oral pilocarpine boosts tear production and proves beneficial for neurogenic keratoconjunctivitis (dry eye) in dogs. <\/strong><\/li>\n
Additionally, topical ophthalmic pilocarpine can be utilized, albeit with a potential for irritation.<\/li>\n
Pilocarpine is rarely<\/strong> used for ophthalmic purposes<\/strong> in cats<\/strong> because of potential toxicity.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Pilocarpine in Dogs and Cats<\/strong><\/h2>\n
Dogs:<\/strong><\/p>\n
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Open-angle glaucoma<\/strong><\/span>: 1 drop per eye of 1% solution q8\u201312h.<\/li>\n
Neurogenic KCS<\/strong><\/span>: 1 drop of 1\u20132% solution per 10 kg p.o. q12h (with food) as the initial dose.<\/li>\n
The dose is increased by 1 drop q2\u20133days until Schirmer tear test (STT) values improve or signs of systemic toxicity are observed (see Adverse Reactions) and then lowered to the previously tolerated dose.<\/li>\n<\/ul>\n
Cats: <\/strong><\/p>\n
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No information is available.<\/li>\n<\/ul>\n
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