{"id":2436,"date":"2023-12-25T14:05:01","date_gmt":"2023-12-25T12:05:01","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2436"},"modified":"2023-12-25T14:05:01","modified_gmt":"2023-12-25T12:05:01","slug":"phenylephrine","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/phenylephrine\/","title":{"rendered":"Phenylephrine"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Phenylephrine In Dogs &amp; Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-2496\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/12\/Phenylephrine.jpg\" alt=\"Phenylephrine In Dogs &amp; Cats: Uses, Dosage and Side Effects\" width=\"800\" height=\"480\" srcset=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/12\/Phenylephrine.jpg 800w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/12\/Phenylephrine-300x180.jpg 300w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/12\/Phenylephrine-768x461.jpg 768w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/12\/Phenylephrine-696x418.jpg 696w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/12\/Phenylephrine-700x420.jpg 700w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>Alpha-1 selective adrenergic agonist that causes peripheral vasoconstriction when given i.v., resulting in increased diastolic and systolic blood pressure, a small decrease in cardiac output and an increased circulation time.<\/li>\n<li>Directly stimulates the alpha-adrenergic receptors in the iris dilator musculature.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Phenylephrine<\/strong><\/h2>\n<ul>\n<li>Phenylephrine is utilized alongside fluid therapy<strong> to address hypotension<\/strong> resulting from drug effects or vascular failure.<\/li>\n<li>When applied topically to the eye, it <strong>induces vasoconstriction and pupil dilation<\/strong>.<\/li>\n<li><strong>Ophthalmic applications<\/strong> involve facilitating mydriasis before intraocular surgery, distinguishing between superficial and deep vasculature, and minimizing haemorrhage during eye surgery.<\/li>\n<li>Additionally, it aids in <strong>diagnosing Horner\u2019s syndrome<\/strong> by assessing the time to pupillary dilation after topical administration, where shorter times suggest lesions closer to the iris.<\/li>\n<li>The use of 10% phenylephrine can <strong>expedite mydriasis<\/strong> in post-ganglionic lesions.<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Phenylephrine in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<p><span style=\"text-decoration: underline;\"><strong>Hypotension:<\/strong><\/span><\/p>\n<ul>\n<li>Correct blood volume then infuse 0.01 mg\/kg very slowly i.v. q15min.<\/li>\n<li>Continuously monitor blood pressure if possible.<\/li>\n<\/ul>\n<p><span style=\"text-decoration: underline;\"><strong>Ophthalmic use<\/strong><\/span>:<\/p>\n<ul>\n<li>1 drop approximately 2 hours before intraocular surgery (for mydriasis).<\/li>\n<li>1 drop as a single dose for vasoconstriction.<\/li>\n<li>1 drop of 1% solution to both eyes for diagnosis of Horner\u2019s syndrome.<\/li>\n<\/ul>\n<p><strong>Cats: <\/strong><\/p>\n<p><strong>Ophthalmic use<\/strong>: as for dogs (NB: ineffective for mydriasis as sole agent).<\/p>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Phenylephrine in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>These include hypertension, tachycardia, and reflex bradycardia.<\/li>\n<li>Extravasation injuries can be serious (necrosis and sloughing).<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Phenylephrine in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>No information is available.<\/li>\n<li>Care in cats and small dogs; use lower concentrate solutions.<\/li>\n<li>Do not apply once ophthalmic surgery has started (to avoid direct arterial absorption).<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>There is a risk of arrhythmias if phenylephrine is used in patients receiving digoxin or with volatile anaesthetic agents.<\/li>\n<li>When used concurrently with oxytocic agents the pressor effects may be enhanced, leading to severe hypertension.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Phenylephrine In Dogs &amp; Cats: Uses, Dosage and Side Effects Overview Alpha-1 selective adrenergic agonist that causes peripheral vasoconstriction when given i.v., resulting in increased diastolic and systolic blood pressure, a small decrease in cardiac output and an increased circulation time. Directly stimulates the alpha-adrenergic receptors in the iris dilator musculature. Uses of Phenylephrine Phenylephrine [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":2496,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-2436","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cardiovascular"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/2436","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=2436"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/2436\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/2496"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=2436"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=2436"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=2436"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}