{"id":2359,"date":"2023-12-02T00:48:55","date_gmt":"2023-12-01T22:48:55","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2359"},"modified":"2023-12-02T00:48:55","modified_gmt":"2023-12-01T22:48:55","slug":"pamidronate","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/pamidronate\/","title":{"rendered":"Pamidronate"},"content":{"rendered":"

Pamidronate In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Pamidronate$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Inhibits osteoclast activity and induces osteoclast apoptosis.<\/li>\n<\/ul>\n
Uses of Pamidronate<\/strong><\/h2>\n
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Treatment of hypercalcaemia<\/strong> (especially associated with vitamin D toxicosis and hypercalcaemia of malignancy).<\/li>\n
Some studies support the use of pamidronate as an adjunctive analgesic for pain associated with bone tumours in dogs<\/strong>.<\/li>\n
In human medicine, it is also used to treat osteolytic lesions<\/strong> and bone pain due to bone metastases associated with breast cancer, multiple myeloma and Paget\u2019s disease.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Pamidronate in Dogs and Cats<\/strong><\/h2>\n
Dogs:<\/strong><\/p>\n
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0.65\u20132 mg\/kg (typically 1 mg\/kg) i.v. slow infusion with NaCl 0.9% over 2\u20134 hours can be repeated q28 days if required.<\/li>\n
Some clinicians advocate 0.9% NaCl i.v. for 2 hours before and after the infusion.<\/li>\n
For cholecalciferol-induced toxicosis, give on days 1 and 4 post-ingestion.<\/li>\n<\/ul>\n
Cats: <\/strong><\/p>\n
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1.0\u20132.0 mg\/kg i.v. slow (over 4 hours) infusion.<\/li>\n<\/ul>\n
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