{"id":2126,"date":"2023-10-23T17:43:47","date_gmt":"2023-10-23T15:43:47","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2126"},"modified":"2023-10-15T17:51:45","modified_gmt":"2023-10-15T15:51:45","slug":"mycophenolate-mofetil-mmf-mycophenolic-acid","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/mycophenolate-mofetil-mmf-mycophenolic-acid\/","title":{"rendered":"Mycophenolate Mofetil (MMF, Mycophenolic acid)"},"content":{"rendered":"

Mycophenolate Mofetil (MMF,
\nMycophenolic acid) In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Mycophenolate$ <\/p>\n\n

Overview<\/strong><\/h2>\n
\n
This compound functions by inhibiting the enzymatic activity responsible for regulating the rate of guanine monophosphate synthesis in the de novo pathway of purine synthesis.<\/li>\n
The previously mentioned route plays a crucial role in the proliferation of B and T cells.<\/li>\n
This activity has similarities to azathioprine.<\/li>\n<\/ul>\n
Uses of Mycophenolate mofetil<\/strong><\/h2>\n
Management of immune-mediated disease including<\/strong>:<\/p>\n
\n
immune-mediated haemolytic anaemia.<\/li>\n
immune-mediated polyarthritis.<\/li>\n
immune-mediated skin disease.<\/li>\n
immune-mediated thrombocytopenia and myasthenia gravis.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Mycophenolate mofetil in Dogs and Cats<\/strong><\/h2>\n
Dogs:<\/strong><\/p>\n
\n
Immune-mediated disease<\/strong><\/span>: 8\u201312 mg\/kg (typically 10 mg\/kg) p.o., i.v. (Give slowly over at least 2 hours) q12h (MMF), the dose can be reduced or given q24h if adverse effects are observed.<\/li>\n
Pemphigus<\/strong><\/span>: 7\u201313 mg\/kg p.o. q8h (MMF).<\/li>\n<\/ul>\n
Cats:<\/strong><\/p>\n
\n
Immune-mediated haemolytic anaemia<\/strong><\/span>: 10 mg\/kg p.o. q12h based on limited experience.<\/li>\n
Other immunosuppressants may be preferable.<\/li>\n<\/ul>\n
\n \n \n