{"id":2107,"date":"2023-09-28T00:03:52","date_gmt":"2023-09-27T21:03:52","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2107"},"modified":"2023-09-28T00:03:52","modified_gmt":"2023-09-27T21:03:52","slug":"minocycline","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/minocycline\/","title":{"rendered":"Minocycline"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Minocycline In Dogs &amp; Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-2251\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/09\/Minocycline.jpg\" alt=\"Minocycline In Dogs &amp; Cats: Uses, Dosage and Side Effects\" width=\"659\" height=\"396\" srcset=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/09\/Minocycline.jpg 800w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/09\/Minocycline-300x180.jpg 300w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/09\/Minocycline-768x461.jpg 768w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/09\/Minocycline-696x418.jpg 696w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/09\/Minocycline-700x420.jpg 700w\" sizes=\"auto, (max-width: 659px) 100vw, 659px\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>By binding to the 30S subunit of the bacterial ribosome, protein synthesis is inhibited in bacteria.<\/li>\n<li>Minocycline is the <strong>tetracycline<\/strong> with the highest lipid solubility and the broadest spectrum of antibacterial, antirickettsial, antimycoplasmal, and antichlamydial activity.<\/li>\n<li>Due to its superior lipid solubility, its clinical efficacy is typically greater than that of other tetracyclines.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Minocycline<\/strong><\/h2>\n<ul>\n<li>Treatment of bacterial, rickettsial, mycoplasmal and chlamydial diseases.<\/li>\n<li>Being extremely lipid-soluble, it penetrates well into prostatic fluid and bronchial secretions.<\/li>\n<li>Use with care in animals with hepatic disease.<\/li>\n<li>If oral dosing in cats, avoid dry pilling as for doxycycline and follow with a water bolus to reduce the risk of oesophageal erosions.<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Minocycline in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs, Cats:<\/strong><\/p>\n<ul>\n<li>5\u201310 mg\/kg p.o. q12h.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Minocycline in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Nausea, vomiting and diarrhoea.<\/li>\n<li>In common with other tetracyclines may cause bone and tooth abnormalities if<br \/>\nused in developing animals.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Minocycline in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>No specific information is available.<\/li>\n<li>Should not be used in pregnancy or young animals.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Its rate of excretion is not affected by renal function as it is cleared by hepatic metabolism and is therefore recommended when tetracyclines are indicated in animals with renal impairment.<\/li>\n<li>Recommended doses for veterinary species have not been clearly defined and recommendations are made on anecdote and a small number of studies.<\/li>\n<li>Absorption of minocycline is reduced by antacids, calcium, magnesium and iron salts and sucralfate.<\/li>\n<li>Phenobarbital and phenytoin may increase its metabolism, decreasing plasma levels.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Minocycline In Dogs &amp; Cats: Uses, Dosage and Side Effects Overview By binding to the 30S subunit of the bacterial ribosome, protein synthesis is inhibited in bacteria. Minocycline is the tetracycline with the highest lipid solubility and the broadest spectrum of antibacterial, antirickettsial, antimycoplasmal, and antichlamydial activity. Due to its superior lipid solubility, its clinical [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":2251,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6,38],"tags":[],"class_list":["post-2107","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-antimicrobials","category-antibacterial"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/2107","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=2107"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/2107\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/2251"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=2107"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=2107"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=2107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}