{"id":2100,"date":"2023-09-17T10:56:31","date_gmt":"2023-09-17T07:56:31","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2100"},"modified":"2023-09-17T08:39:10","modified_gmt":"2023-09-17T05:39:10","slug":"midazolam","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/midazolam\/","title":{"rendered":"Midazolam"},"content":{"rendered":"

Midazolam In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Midazolam$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Increases the effect of GABA on the GABA A<\/strong> receptor, resulting in neural inhibition, sedation, anxiolytic effects, hypnotic effects, amnesia, muscle relaxation, and anticonvulsant effects.<\/li>\n
It is more potent, has a shorter onset and duration of action (<1 hour in canines), and is less irritating to tissues than diazepam.<\/li>\n<\/ul>\n
Uses of Midazolam<\/strong><\/h2>\n
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Provides sedation with amnesia; as part of a premedication regime or as part of combined anaesthetic protocols.<\/li>\n
Emergency control of epileptic seizures (including status epilepticus).<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Midazolam in Dogs and Cats<\/strong><\/h2>\n
Dogs, Cats:<\/strong><\/p>\n
Emergency management of seizures including status epilepticus<\/strong>:<\/p>\n
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bolus dose of 0.2\u20130.3 mg\/kg i.v. or intrarectally if venous access is not available.<\/li>\n
Time to onset of clinical effect is rapid for i.v. use, therefore, repeat q10min if there is no clinical effect up to 3 times.<\/li>\n
Midazolam may be used in conjunction with diazepam for emergency control of seizures.<\/li>\n
In dogs<\/strong>, additional doses may be administered if appropriate supportive care facilities are available (for support of respiration).<\/li>\n
Once the seizures have been controlled, the dog can be maintained on a constant i.v. infusion of 0.3 mg\/kg\/h.<\/li>\n<\/ul>\n
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