{"id":2096,"date":"2023-09-16T21:56:28","date_gmt":"2023-09-16T18:56:28","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2096"},"modified":"2023-09-12T22:25:36","modified_gmt":"2023-09-12T19:25:36","slug":"mexiletine","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/mexiletine\/","title":{"rendered":"Mexiletine"},"content":{"rendered":"

Mexiletine In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Mexiletine$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Antiarrhythmic agent<\/strong> of class 1b, similar to lidocaine.<\/li>\n
It inhibits the inward sodium current (fast sodium channel), slowing the rate of rise of the action potential.<\/li>\n
It reduces automaticity, action potential duration, and effective refractory period in Purkinje fibres.<\/li>\n<\/ul>\n
Uses of Mexiletine<\/strong><\/h2>\n
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Management of rapid or hemodynamically significant ventricular arrhythmias, such as frequent complex ventricular premature complexes or ventricular tachycardia, has been demonstrated.<\/li>\n
Effective in certain dogs with supraventricular tachycardia caused by the presence of an accessory conduction pathway, also known as a bypass tract.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Mexiletine in Dogs and Cats<\/strong><\/h2>\n
Dogs:<\/strong><\/p>\n
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Oral<\/span>: 4\u20138 mg\/kg p.o. q8\u201312h.<\/li>\n
Dose for i.v. not established for dogs.<\/li>\n<\/ul>\n
Cats:<\/strong><\/p>\n
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No information is available.<\/li>\n<\/ul>\n
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