{"id":2009,"date":"2023-09-04T21:09:10","date_gmt":"2023-09-04T18:09:10","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=2009"},"modified":"2023-08-31T21:16:11","modified_gmt":"2023-08-31T18:16:11","slug":"maropitant","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/maropitant\/","title":{"rendered":"Maropitant"},"content":{"rendered":"

Maropitant In Dogs & Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Maropitant$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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The mechanism of action involves the inhibition of the vomiting reflex<\/strong> through the blockade of NK-1 receptors located in the medullary vomiting centre.<\/li>\n
The compound in question has a high degree of protein binding and possesses a prolonged duration of activity<\/strong> lasting for a period of 24 hours.<\/li>\n
There is currently no evidence<\/strong> to suggest that maropitant possesses any prokinetic properties.<\/strong><\/li>\n<\/ul>\n
Uses of Maropitant<\/strong><\/h2>\n
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The management and prophylaxis of emesis in canines<\/strong>\u00a0encompass cases induced by chemotherapy and motion sickness (although not all medications are explicitly approved for these indications).<\/li>\n
Maropitant exhibits favourable tolerability and demonstrates robust antiemetic efficacy<\/strong> in feline.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Maropitant in Dogs and Cats<\/strong><\/h2>\n
Dogs:<\/strong><\/p>\n
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Vomiting:<\/strong><\/span> 1 mg\/kg i.v. or s.c. q24h or 2 mg\/kg p.o. q24h.<\/li>\n
Motion sickness<\/strong><\/span>: tablets at a dose rate of 8 mg\/kg q24h for a maximum of 2 days given 1 hour before the journey.<\/li>\n
Prevention of chemotherapy-induced emesis:<\/strong><\/span> 1 mg\/kg s.c. q24h or 2 mg\/kg p.o. q24h, given at least 1 hour in advance.<\/li>\n<\/ul>\n
Cats<\/strong>:<\/p>\n
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Vomiting<\/strong><\/span>: 1 mg\/kg i.v., s.c. or p.o. q24h.<\/li>\n<\/ul>\n
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