{"id":1906,"date":"2023-08-14T14:12:48","date_gmt":"2023-08-14T11:12:48","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=1906"},"modified":"2023-08-12T17:17:18","modified_gmt":"2023-08-12T14:17:18","slug":"lipid-infusions","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/lipid-infusions\/","title":{"rendered":"Lipid Infusions"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Lipid infusions In Dogs &amp; Cats: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1940 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/08\/Lipid-Infusions.jpg\" alt=\"Lipid infusions In Dogs &amp; Cats: Uses, Dosage and Side Effects\" width=\"800\" height=\"480\" srcset=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/08\/Lipid-Infusions.jpg 800w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/08\/Lipid-Infusions-300x180.jpg 300w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/08\/Lipid-Infusions-768x461.jpg 768w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/08\/Lipid-Infusions-696x418.jpg 696w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/08\/Lipid-Infusions-700x420.jpg 700w\" sizes=\"auto, (max-width: 800px) 100vw, 800px\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>Support intermediary metabolism.<\/li>\n<li>Reverse negative energy balance.<\/li>\n<li>Provide some essential fatty acids and sequester lipid-soluble substances in the plasma compartment.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Lipid infusions<\/strong><\/h2>\n<ul>\n<li>Used parenterally in animals receiving nutritional support, to provide<strong> fat for energy production<\/strong> and <strong>essential fatty acids<\/strong> for <strong>cellular metabolism<\/strong> and <strong>support of the immune system<\/strong>.<\/li>\n<li>It can also <span style=\"text-decoration: underline;\"><strong>bind lipid-soluble toxins<\/strong><\/span> such as <strong>unintentional intravenous administration of bupivacaine or avermectins.<\/strong><\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Lipid Infusions in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><\/p>\n<ul>\n<li><span style=\"text-decoration: underline;\"><strong>Parenteral nutrition<\/strong><\/span>: the amount required will be governed by the patient\u2019s physiological status and whether partial or total parenteral nutrition is provided. <strong>Generally,<\/strong> lipid infusions are used to supply 30% (partial peripheral) to 40\u201360% of energy requirements.<\/li>\n<\/ul>\n<p><strong>Cats:<\/strong><\/p>\n<ul>\n<li><span style=\"text-decoration: underline;\"><strong>Parental nutrition<\/strong><\/span>: the amount required will be governed by the patient\u2019s physiological status and tolerance of lipids.<br \/>\n<strong>Generally,<\/strong> amino acids in cats provide peripheral parenteral nutrition, and lipids are used as an energy source in a nutrient admixture for infusion through central venous access (total parenteral nutrition) to supply 40\u201360% of energy requirements.<\/li>\n<\/ul>\n<p><strong>Dogs, Cats:<\/strong><\/p>\n<p><strong><span style=\"text-decoration: underline;\">Treatment of lipid-soluble toxicosis such as ivermectin<\/span> <span style=\"text-decoration: underline;\">or moxidectin toxicosis<\/span>:<\/strong><\/p>\n<ul>\n<li>administer 1.5\u20135 ml\/kg i.v. of 20% lipid solution as a bolus, followed by 0.25\u20130.50 ml\/kg\/min i.v. infusion for 30\u201360 min.<\/li>\n<li>Boluses of 1.5 ml\/kg can be repeated.<\/li>\n<li>Infusions of 0.5 ml\/kg\/min can be administered for a maximum of 24 hours.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Lipid Infusions in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Occasional <strong>febrile episodes<\/strong> are mainly seen with 20% emulsions.<\/li>\n<li>20% and 30% lipid products have a higher rate of complications including <strong>vasculitis<\/strong>, <strong>thrombosis<\/strong>, <strong>fever<\/strong> and other metabolic complications and are not recommended.<\/li>\n<li>Rare <strong>anaphylactic responses<\/strong> are reported in humans.<\/li>\n<li>Early reports of <strong>hepatic failure<\/strong>, <strong>pancreatitis<\/strong>, <strong>cardiac arrest<\/strong> and thrombocytopenia<br \/>\ndetailed in human literature appear to have been complications of prolonged treatment.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Lipid Infusions in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Insulin resistance (e.g. diabetes mellitus) and hyperlipidaemia.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Lipid emulsions are<strong> isosmolar<\/strong> with plasma and can be infused into a peripheral vein to provide parenteral nutrition.<\/li>\n<li>Use with<strong> caution<\/strong> in patients with known <strong>insulin resistance<\/strong> or at risk of developing pancreatitis.<\/li>\n<li>Lines for i.v. parenteral feeding (lipid, glucose, amino acids or nutrient admixtures) should be dedicated for that use alone and should not be used for administration of other medications.<\/li>\n<li>Interference with biochemical measurements, such as those for blood gases and calcium, may occur if samples are taken before fat has been cleared.<\/li>\n<li>Daily checks are necessary to ensure complete clearance from the plasma in conditions where fat metabolism may be disturbed.<\/li>\n<li>Additives may only be mixed with fat emulsions where compatibility is known.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Lipid infusions In Dogs &amp; Cats: Uses, Dosage and Side Effects Overview Support intermediary metabolism. Reverse negative energy balance. Provide some essential fatty acids and sequester lipid-soluble substances in the plasma compartment. Uses of Lipid infusions Used parenterally in animals receiving nutritional support, to provide fat for energy production and essential fatty acids for cellular [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1940,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[28],"tags":[],"class_list":["post-1906","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-supportive-treatments"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/1906","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=1906"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/1906\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1940"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=1906"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=1906"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=1906"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}