{"id":1541,"date":"2023-05-17T08:13:36","date_gmt":"2023-05-17T06:13:36","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=1541"},"modified":"2023-05-17T11:39:03","modified_gmt":"2023-05-17T09:39:03","slug":"fluralaner","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/fluralaner\/","title":{"rendered":"Fluralaner"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Fluralaner: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-1584 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluralaner.jpg\" alt=\"\" width=\"661\" height=\"397\" srcset=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluralaner.jpg 800w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluralaner-300x180.jpg 300w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluralaner-768x461.jpg 768w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluralaner-696x418.jpg 696w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluralaner-700x420.jpg 700w\" sizes=\"auto, (max-width: 661px) 100vw, 661px\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>Fluralaner acts at <strong>ligand-gated chloride channels<\/strong>, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby <strong>blocking the pre-and post-synaptic transfer of chloride ions across cell membranes<\/strong>.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Fluralaner<\/strong><\/h2>\n<ul>\n<li>Treatment of <strong>fleas and ticks<\/strong> in dogs\/cats.<\/li>\n<li>Treatment of <strong>ear mite<\/strong> (Otodectes cynotis) in cats.<\/li>\n<li>Fluralaner has an action against <strong>Demodex mites.<\/strong><\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Fluralaner in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs: <\/strong><\/p>\n<ul>\n<li>25\u201356 mg fluralaner\/kg p.o. q 3 months or apply 1 pipette per dog according to body weight q 3 months.<\/li>\n<\/ul>\n<p><strong>Cats: <\/strong><\/p>\n<ul>\n<li>Apply 1 pipette per cat according to body weight q 3 months.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Fluralaner in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li><strong>Oral product dogs:<\/strong> Mild GI signs may occur; convulsions and lethargy have been reported very rarely.<\/li>\n<li><strong>Spot-on:<\/strong> erythema, and alopecia at the application site.<\/li>\n<li><strong>Cats:<\/strong> apathy, tremors, anorexia, vomiting, hypersalivation.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Fluralaner in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Do not use in dogs &lt;8 weeks or &lt;2 kg.<\/li>\n<li>Should not be used on kittens &lt;11 weeks and\/or cats weighing less than 1.2 kg.<\/li>\n<li>Use with caution in dogs with pre-existing epilepsy.<\/li>\n<li>The product should not be administered at intervals shorter than 8 weeks.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Fluralaner is highly bound to plasma proteins and might compete with other highly bound active substances such as NSAIDs and the coumarin derivative warfarin.<\/li>\n<li><strong>Onset of action:<\/strong> fleas within 8 hours and ticks within 12 hours (Ixodes ricinus).<\/li>\n<li>Immediate and persistent tick-killing activity for 12 weeks for <em>Ixodes ricinus<\/em>, <em>Dermacentor reticulatus<\/em> and <em>D. variabilis<\/em>, 8 weeks for <em>Rhipicephalus sanguineus<\/em>.<\/li>\n<li>Parasites need to start feeding on the host to become exposed to fluralaner; therefore the risk of the transmission of parasite-borne diseases cannot be excluded.<\/li>\n<li>Can be used in breeding, pregnant and lactating dogs.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Fluralaner: Uses, Dosage and Side Effects Overview Fluralaner acts at ligand-gated chloride channels, in particular those gated by the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking the pre-and post-synaptic transfer of chloride ions across cell membranes. Uses of Fluralaner Treatment of fleas and ticks in dogs\/cats. Treatment of ear mite (Otodectes cynotis) in cats. Fluralaner has [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1584,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[32,10],"tags":[],"class_list":["post-1541","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-antiparasitic","category-fleas-and-ticks"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/1541","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=1541"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/1541\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1584"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=1541"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=1541"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=1541"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}