{"id":1462,"date":"2023-05-13T21:07:29","date_gmt":"2023-05-13T19:07:29","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=1462"},"modified":"2023-05-13T21:07:29","modified_gmt":"2023-05-13T19:07:29","slug":"flucytosine","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/flucytosine\/","title":{"rendered":"Flucytosine"},"content":{"rendered":"

Flucytosine: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Flucytosine:$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Fungal cells<\/strong> convert flucytosine (5-FC) into 5-fluorouracil (5-FU), which inhibits DNA and RNA synthesis in the cell. <\/strong><\/li>\n
Mammalian cells are spared.<\/li>\n
Penetrates well into cerebrospinal fluid.<\/li>\n<\/ul>\n
Uses of Flucytosine<\/strong><\/h2>\n
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Treatment of cryptococcosis<\/strong> (often in conjunction with amphotericin B or itraconazole) particularly if involving meninges; systemic and urinary yeast infections<\/strong> (e.g. candidiasis).<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Flucytosine in Dogs and Cats<\/strong><\/h2>\n
Dogs:<\/strong><\/p>\n
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Fungal infections: 25\u201335 mg\/kg i.v. q8h or 50\u201365 mg\/kg p.o. q8h.<\/li>\n<\/ul>\n
Cats:<\/strong><\/p>\n
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Fungal infections: 25\u201350 mg\/kg i.v. q6h or 50\u201365 mg\/kg p.o. q8h.<\/li>\n<\/ul>\n
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