{"id":1459,"date":"2023-05-14T21:00:18","date_gmt":"2023-05-14T19:00:18","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=1459"},"modified":"2023-05-13T21:04:34","modified_gmt":"2023-05-13T19:04:34","slug":"fluconazole","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/fluconazole\/","title":{"rendered":"Fluconazole"},"content":{"rendered":"<p style=\"text-align: center; font-size: 24px; font-family: sans-serif;\"><strong>Fluconazole: Uses, Dosage and Side Effects<\/strong><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-1567 aligncenter\" src=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluconazole.jpg\" alt=\"Fluconazole: Uses, Dosage and Side Effects\" width=\"659\" height=\"396\" srcset=\"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluconazole.jpg 800w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluconazole-300x180.jpg 300w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluconazole-768x461.jpg 768w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluconazole-696x418.jpg 696w, https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-content\/uploads\/2023\/05\/Fluconazole-700x420.jpg 700w\" sizes=\"auto, (max-width: 659px) 100vw, 659px\" \/><\/p>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Overview<\/strong><\/h2>\n<ul>\n<li>Inhibition of ergosterol synthesis in fungal cell membranes, resulting in increased cell wall permeability and cellular content leakage.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Uses of Fluconazole<\/strong><\/h2>\n<ul>\n<li>Effective against Blastomyces, Candida, Cryptococcus, Coccidioides, Histoplasma and Microsporum canis infections and variably effective against Aspergillus and Penicillium<br \/>\ninfections.<\/li>\n<\/ul>\n<div class='code-block code-block-12' style='margin: 8px auto; text-align: center; display: block; clear: both;'>\n<a target=\"_blank\" href=\"https:\/\/www.vet-ebooks.com\/premium-memberships\/\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-17003\" src=\"https:\/\/www.vet-ebooks.com\/wp-content\/uploads\/2024\/10\/veterinary-books-1.jpg\" width=\"480\" height=\"98\"  alt=\"Vet Books\"\/><\/a><\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Dose of Fluconazole in Dogs and Cats<\/strong><\/h2>\n<p><strong>Dogs:<\/strong><br \/>\n<strong>\u2022 Fungal infections:<\/strong> 2.5\u20135 mg\/kg p.o. q12h.<\/p>\n<p><strong>Cats:<\/strong><\/p>\n<ul>\n<li><strong>Ocular\/CNS cryptococcosis:<\/strong> 50 mg\/cat i.v. infusion, p.o. q24h.<\/li>\n<li><strong>Systemic infections<\/strong>: give double the calculated dose on day 1. Doses up to 100 mg\/cat q12h are sometimes used for systemic\/ CNS Cryptococcus infection.<\/li>\n<li><strong>Dermatophytosis, nasal cryptococcosis:<\/strong> 5 mg\/kg p.o. q24h.<\/li>\n<li><strong>For dermatophytosis<\/strong>, administer for 3 periods of 7 days, with 7 days without treatment in between.<\/li>\n<\/ul>\n<p><strong>Dogs, Cats<\/strong>:<\/p>\n<ul>\n<li><strong>Urinary candidiasis:<\/strong> 5\u201310 mg\/kg q24h.<\/li>\n<\/ul>\n<div class='code-block code-block-2' style='margin: 8px auto 8px 0; text-align: left; display: block; clear: both;'>\n <html>\n  <head>\n    <style>\n    \n \n      #calculator {\n        width: 100%;\n        margin: auto;\n      }\n      \n      @media (max-width: 600px) {\n        #calculator {\n          width: 90%;\n        }\n      }\n      \n      #calculator23 {\n        display: block;\n        margin-bottom: 8px;\n        font-size: 14px;\nfont-family: sans-serif;font-weight:600;\n      }\n      \n      #calculator24{\n        width: 100%;\n        padding: 12px 20px;\n        margin: 8px 0;\n        box-sizing: border-box;\n        border: 2px solid #ccc;\n        border-radius: 4px;\n      }\n      \n      #calculator25 {\n        width: 100%;\n    background-color: #fabd14;\n    color: white;\n    padding: 11px 18px;\n    margin: 5px 0;\n    border: none;\n    border-radius: 4px;\n    cursor: pointer;\n    font-size: 15px;\n    font-family: sans-serif;\n    font-weight: 600;\n}\n      }\n      \n      #result {\n        font-size: 18px;\n        font-weight: bold;\n      }\n    <\/style>\n  <\/head>\n  <body>\n  \n \n\n  <h2 style=\"border-bottom: 2px #fff7e6 solid;\" class=\"cd-section-title\"><span><strong>Drug Dosage Calculator<\/strong><\/span><\/h2>\n    <form id=\"calculator\">\n      <label id=\"calculator23\" for=\"weight\">Animal Weight (kg):<\/label>\n      <input type=\"text\" id=\"weight\" name=\"weight\" id=\"calculator24\">\n      <label for=\"dose\" id=\"calculator23\">Drug Dose (mg\/kg):<\/label>\n      <input type=\"text\" id=\"dose\" name=\"dose\" id=\"calculator24\">\n      <label for=\"concentration\" id=\"calculator23\">Drug Concentration (mg\/mL or mg\/tablet):<\/label>\n      <input type=\"text\" id=\"concentration\" name=\"concentration\" id=\"calculator24\">\n      <button type=\"button\" onclick=\"calculate()\" id=\"calculator25\">Calculate<\/button>\n    <\/form> \n    \n    <p style=\"\n    font-size: 13px;\n    font-weight: 600;\n    font-family: sans-serif;\n    background: #444;\n    padding: 5px;\n    border-radius: 5px;\n    color: #fff;\n\">You Should Give: <span id=\"result\"><\/span><\/p>\n\n\n    \n    <script>\n      function calculateDose(weight, dose, concentration) {\n        return (weight * dose \/ concentration).toFixed(2);\n      }\n      \n      function calculate() {\n        let weight = document.getElementById(\"weight\").value;\n        let dose = document.getElementById(\"dose\").value;\n        let concentration = document.getElementById(\"concentration\").value;\n        let result = calculateDose(weight, dose, concentration);\n        document.getElementById(\"result\").innerHTML = result + \" mL or tablet \";\n      }\n    <\/script>\n  <\/body>\n<\/html>\n<\/div>\n\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Side Effects of Fluconazole in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Adverse effects may include nausea and diarrhoea.<\/li>\n<li>May be hepatotoxic.<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Contraindications of Fluconazole in Dogs and Cats<\/strong><\/h2>\n<ul>\n<li>Do not use in pregnant\/lactating animals<\/li>\n<\/ul>\n<h2 style=\"border-bottom: 2px #fabd14 solid; font-size: 20px;\"><strong>Some Notes:<\/strong><\/h2>\n<ul>\n<li>Therapeutic concentrations are<strong> reached in the CNS and respiratory tract. <\/strong><\/li>\n<li>The kidney excretes it, resulting in <strong>elevated concentrations in urine<\/strong>.<\/li>\n<li>Reduce dosage for animals with impaired renal function and hepatic disease.<\/li>\n<li>This medication should be taken <strong>until clinical symptoms have resolved<\/strong> and the organism is no longer present; in some cases, this may take up to two months.<\/li>\n<li>Fluconazole (due to inhibition of cytochrome P450-dependent liver enzymes) may <strong>increase plasma theophylline concentrations. <\/strong><\/li>\n<li>Fluconazole <strong>increases ciclosporin blood levels.<\/strong><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Fluconazole: Uses, Dosage and Side Effects Overview Inhibition of ergosterol synthesis in fungal cell membranes, resulting in increased cell wall permeability and cellular content leakage. Uses of Fluconazole Effective against Blastomyces, Candida, Cryptococcus, Coccidioides, Histoplasma and Microsporum canis infections and variably effective against Aspergillus and Penicillium infections. Dose of Fluconazole in Dogs and Cats Dogs: [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":1567,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1459","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/1459","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/comments?post=1459"}],"version-history":[{"count":0,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/posts\/1459\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media\/1567"}],"wp:attachment":[{"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/media?parent=1459"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/categories?post=1459"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/wp-json\/wp\/v2\/tags?post=1459"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}