{"id":1244,"date":"2023-05-08T22:17:06","date_gmt":"2023-05-08T20:17:06","guid":{"rendered":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/?p=1244"},"modified":"2023-05-08T22:17:06","modified_gmt":"2023-05-08T20:17:06","slug":"enrofloxacin","status":"publish","type":"post","link":"https:\/\/www.vet-ebooks.com\/vetdrugslist\/enrofloxacin\/","title":{"rendered":"Enrofloxacin"},"content":{"rendered":"

Enrofloxacin: Uses, Dosage and Side Effects<\/strong><\/p>\n

$\"Enrofloxacin:$ <\/p>\n\n

Overview<\/strong><\/h2>\n
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Enrofloxacin is a concentration-dependent antibiotic that prevents bacterial DNA gyrase activity.<\/li>\n
Pulse dosing strategies may be helpful against Gram-negative bacteria in particular.<\/li>\n<\/ul>\n
Uses of Enrofloxacin<\/strong><\/h2>\n
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Fluoroquinolones should be reserved<\/strong> for infections where culture and sensitivity testing indicate a clinical response and lower-tier antimicrobials fail.<\/li>\n
Active against<\/strong> Mycoplasma, Pasteurella, Staphylococcus, Pseudomonas aeruginosa, Klebsiella, Escherichia coli, Mycobacterium, Proteus, and Salmonella.<\/li>\n
Poor against<\/strong> obligatory anaerobes.<\/li>\n
Fluoroquinolones treat soft tissue<\/strong>, urogenital<\/strong> (including prostate), and cutaneous<\/strong> infections because they are lipophilic and reach high cell concentrations.<\/li>\n
Enrofloxacin, clarithromycin, and rifampin treat non-tubercular mycobacterial<\/strong> disease.<\/li>\n
In severe sepsis, i.v. the\u00a0administration is allowed.<\/li>\n
Dilute to 10 times the volume with 0.9% sodium chloride and deliver slowly (35\u201345 minutes) because the carrier contains potassium.<\/li>\n<\/ul>\n
\n $\"Vet$ <\/a><\/div>\n\n
Dose of Enrofloxacin in Dogs and Cats<\/strong><\/h2>\n
Dogs:<\/strong><\/p>\n
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5 mg\/kg s.c. q24h. Higher doses (10 mg\/kg q24h) should be considered for certain sites, including prostatitis.<\/li>\n
Even higher doses may be necessary for certain isolates of Pseudomonas aeruginosa.<\/li>\n
Contact the manufacturer to discuss individual cases.<\/li>\n<\/ul>\n
Cats:<\/strong><\/p>\n
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5 mg\/kg s.c. q24h; 2.5 mg\/kg p.o. q12h or 5 mg\/kg p.o. q24h<\/li>\n<\/ul>\n
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